ALI-BIXBY-LEMMON COLLECTIVE
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    • PNS vs CNS Regeneration
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    • Group Photos >
      • PAMM 160728
      • ProjectRock 190524
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    • Abdiel Badillo-Martinez
    • Yania Martinez, VVC Core >
      • Yania's Monarch
    • Yan Shi, M.S. Imaging and HCA Core
    • Macarena Vergara
    • Former Lab Members >
      • Sam Beckerman, MD/PhD student
      • Julia Brzac
      • Willi Buchser, PhD
      • Nathaniel Cleri
      • Danny Cooper, Ph.D.
      • Danny Cabrera
      • Pingping Chen, MD/PhD, Viral Vector Core
      • Matt Danzi, PhD student
      • Ellie Dawson
      • Roberto E Diaz
      • Kireeti Dulla
      • Laetitia Francelle, Ph.D.
      • Nathan Fox
      • Jared Gans, M.D.
      • Juliana Hemela
      • Pingping Jai, M.S. Viral Vector Core
      • Victor Jann
      • Danny L. John, MS1
      • Ryohei Kurosawa
      • Lyndah Lovell
      • Jeffrey Lowell
      • Nick O'Neill, PhD student
      • Kim Madhwani
      • Kar Men Mah, Ph.D.
      • Dario Motti, PhD
      • Melissa Munoz
      • Maya Murry: Computer Science REU
      • Michael Ortega
      • Marcos Rivas: HHMI SURF
      • Saloni Mehta, PhD student
      • Sevika Singh
      • Tatiana Slepak, M.S.
      • Robin Smith, PhD
      • Moya Tomlin, MS2
      • Enjolie Vadella
      • Eli Weaver, Lab Manager
      • Giulia Zunino, Ph.D.
  • Resources
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Weebly was bought out by Square.  Square is focused on on-line business.  It appears that the viability of LemBixLab.net is limited.  updateS of this website will be less frequent. 


More transitions.  Abdile no longer works for thE Ali-Bixby-Lemmon Team (ABL - this acronym needs some work).  That is the bad news.  Now the good News.  Abdile is a PhD student and Hassan is his mentor.  Very cool.  His new lab coat has a decent fit in the arms.  The shoulders and chest?  Not so much.

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Yesterday was Meli's last day.  She is going to continue her education to persue her dreams.  That is fantastic, but we will miss her terribly.  The sunbeams she brings everywhere with her can not be replaced.   😞

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We obsEsS about data visualization a LOT.  For years, my favorite figure of high dimensional data was made by Willi Buchser and is in his Molecular Systems Biology paper (Figure 3).  Nick now has my new favorite Figure of a mouse paw graBbing a food pellet.  The black dot is the pellet.  The other dots are the tips of the mouse's fingers.  Wow.  By the way, that movement takes 200 milliseconds. 😳

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Today (August 1, 2022) Nick O'Neill transformed into Dr. Nick O'Neill. He successfully defended his Dissertation titled "Distinguishing Between Strategic Compensation and Functional Recovery after Spinal Cord Injury”.  The Entire LembixAli Consortium is so happy that Nick has been rewarded for all his hard work.  A special shout out to Abdiel for being Nick's right-paw man through all the behavior and anatomy.

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FRiday, JUly 29th was the last day of the Computer Science Dept. REU program.  Ellie and Julia presented posters on their projects.  Julia won Second Place for her poster.  Is that great or what!?  They both got lots of help from Nick and Hassan.  Nice.  We are sorry to see them go.  Really delightful students.


in early june i foolishly agreed to give a talk in person in kyoto rather than do it remotely, as originally planed.  Fortunately I was able to get my visa in the nick of time and meet all the health clearance requirements.  it was great to see old friends like Kyoko Itoh, Shinji Fushiki, Ritsuko Pooh, and Yukiko Nakamura.

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On June 1, Hassan was promoted to Associate research professor.  We are all very proud of his various successes. 

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Kar Men et al's paper on RO48 was on-line last night (5/16/22)

This paper is the culmination of a large collaboration with Xiao-Ming Xu and Jae Lee and the data was a critical part of the package that resulted in our team getting the Blueprint Neurotherapeutics Grant.  A special shout out to Wei Wu (co-first author with Kar Men), Yan Sun, Qi Han and Ying Ding.  Click on the first image to go to the paper.
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Matt Danzi, John and I are co-authors on a paper in Science that came out today (5/13/2022).  The di Giovanni lab is the principle lab on this project.  

We have been collaborating with them for years (scroll down to see other papers).  Sometimes there was lab work, but mostly it was informatics provided by Matt.  My goodness!  John and I have co-authored 15 papers with Matt.  What a star!!!   Click on the images to navigate to the papers.
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Science even had a perspective on it.
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Nick, Kar Men and Abdiel's paper using deeplabcuT to analyze the SUBTLETIES of the classic pellet RETRIEVAL assay was accepted yesterday evening (4/13/22).  We are super EXCITED about this

The team used high speed videos to measure pronation and the path of paw movement before and after injury.  They came to some interesting conclusions.  

The paper appeared on line today (4/21/2022)

https://www.sciencedirect.com/science/article/pii/S0014488622001108



"Developing a kinase inhibitor drug to treat spinal cord injury"   ​1 UG3 NS124630-01

Third time’s the charm.  Hassan, John, Jae, Alberto and I submitted a proposal to the NINDS Blueprint Neurotherapeutics Program three times over three years, and we got our notice of award today!  This gives us the opportunity to take our kinase inhibitor with remarkable polypharmacology into a program to develop a drug for spinal cord injury.  A dream scenario for any scientist.  Also, a wonderful example of team science.  Hassan is the contact-PI and there is no one on the planet who could be a better leader for this project.  Thanks to all the LemBixLab members past and present whose rigorous science enabled this.  Also, a shout out to Xiao-Ming Xu, Wei Wu, Yan Sun and Ying Ding. BTW, Yan Shi has been running the phenotypic assays through our HCS microscopes for our lab since 2005.  Thank you, Yan!
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2021 LemBixLab Christmas Photo

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Yesterday (Oct. 20, 2021), I represented our lab at the 2021 International Neural Regeneration Symposium in Nantong, China.  I admit I was sitting in my home office in Coconut Grove. My research talk was given in video FORMAT along with the two other Keynote Speakers, Susan Harkema and Zhigang He.  Later, at a Q&A session, our lab's work was recognized by a LIFETIME ACHIEVEMENT Award.  I was very proud to represent John, Hassan and our other lab members (past and present).   I pointed out how important staff scientists are to our lab's success. THANK YOU GUANGHUI CHENG, PINGPING CHEN, ABDIEL BADILIO-MARTINEZ, WENDY ELMSLIE, PINGPING JAI, Yuanyuan Jai, GUERLINE LAMBERT, YANIA MARTINEZ, MELISSA MUNOZ, MARYANNE PENDERGAST, YAN SHI, TATIANA SLEPAK, DINARA STRIKIS, AND LAST BUT NOT LEAST, ELI WEAVER.

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A few people watched the event online - oveR 9600 people  - nuts

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At the last INRS workshop I ran, I was excited because about 200 people attended.  I had no Idea what the 2 virtual workshops (Machine Learning for Dummies/Biologists and Light Sheet Microscopy) were going to be like but I was hoping for at least 200 people.   I was watching the Zoom count and it was inching past 150, so I sent a chat to one of the organizers.  She told me most people in China were WATCHING on a different platform and there were 3500 people watching.   The numbers kept going up.  UNBELIEVABLE.


A couple of years ago vance proposed two workshops for the 2020 INRS meeting.  It seemed like a good idea at the time.  The meeting has been postponed at least 4 times and now is virtual for non-Chinese.   How will I stay awake tonight until 12 PM tonight? - arrggg

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Maya Murray, our amazing physics undergrad from Cornell who worked in the lab last summer presented her work at the National Council on Undergraduate Research Symposium on 10/25/2021.   Well Done Maya!

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John and Vance are part of a new U24 grant with Adam, Karim, Jeff, Maryann and a host of SCI and TBI experts.  The Pan-Neurotrauma Data Commons will serve as a data REPOSITORY.  We will work with our friends Alison Callahan and Ubbo Visser to build a new ontology.  Adam came up with the fun PANORAUMA name.    :-)

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The Miller School of Medicine is investing in drug discovery.   We now have an operational Opera Phenix Plus.  Bring on those 3D models of disease!

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Marcos, our HHMI Summer Scholar, is on his way to Emory in the FAll (Full ride!).  This week he learned he has been awarded a PRESTIGIOUS Hispanic SCHOLARSHIP.  Well done Marcos! 

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Jeff, Nick and Matt's paper came out today in SLAS Discovery.  It identifies  Transcription Factors that are part of the molecular response to our favorite kinase inhibitor, RO48, which drives axon growth

​doi/10.1177/24725552211026270
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on 5/27/21 the new PerkinElmer Phenix Plus arrived.  Super excited to get this massive upgrade for phenotypic Screening.  Install next week.  Need some wood?

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Yesterday (5/5/21) was the U.M. Neuroscience Program Retreat. Nick O'NeilL won 2nd place for best presentation.  Way to go Nick!  There was a panel with 7 alumni talking about their post-U.M. careers.  3/7 were LemBixLab graduates: AnDrea, Saloni and Willie.  JOhn and I are very lucky to have had them in our lab.


My talk about regeneration in 2071 with Wolf Tetzlaff is over.  Karina Branson made a cool illustration of the talk.  It featured the premier of ERic Lemmon's sonification of single cell RNA-seq data from Jae Lee and James Choi.  The PDF of the slide deck is also available.

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Kar Men's review on behavioral testing came out - a cool collaboration with Keith Fenrich and Karim Fouad

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My friend, Ed Lachina, at Intelligent Imaging Innovations (3i), shared a photo of their new light sheet microscope for very large specimens. 1.8 liters of index matching media. This is sick!  Can't wait to see the images it collects.   

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On Feb.4, 2021 WAZE routed me home from the medical campus via surface streets INSTEAD of on I-95.  It did it again on Feb. 5.  This is the first time this has happened since Feb. of 2020.  It is certainly consistent with the data in Monod et al, Science, Feb 2 issue.  This is not so great, given the current immunization status of Floridians.


On January 20, members of our team celebrated the INAUGURATION of an administration that BELIEVES in SCIENCE. It is worth pointing out that while 5/6 are  Citizens (the other is a green card holder), the countries of ORIGIN are Lebanon, ColumbiA, China, Malaysia, Cuba and the U.S.A. 

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The latest data from CHOP makes the post from June below look ......  What a catastrophe.  SOCIAL distancing at 5%.  Miami, you can do better.   

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I am attending the Zusman Workshop, March 3-5, 2021.  I can't wait to hear Wolfram Tetzlaff describe what regeneration will look like in 2071.  Registration can be found here.  

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Last year the editor of J. Neuroscience asked me to write about a paper I had in the first issue of the Journal in 1981.   The story came out last week in the 40th ANNIVERSARY issue.  It is an honor to have been asked to do this.

The Life of a Trailing Spouse. Lemmon VP.  J Neurosci. 2021 Jan 6;41(1):3-10. doi: 10.1523/JNEUROSCI.2874-20.2020.PMID: 33408132 


Yet another paper with the Di Giovanni Lab.  You can find it Here 

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Jeffrey Lowell SUCCESSFULLY defended his PhD DISSERTATION today.  Well Done Jeff!

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Our paper with Derek Welsbie and Don Zack is out - Super-excited

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CAn't wait for Jan. 20, 2021!


Jeff and Kar men's paper on AVV-8 transduction altered by ph came out in PubMed today.  Nice job Team.  Special Thanks to Meli, Yania and Yan!

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Chris Austin - Head of NCATS - said this today at the Assay Guidance Manual Virtual Workshop.   What kind of R&R do you have in your wallet?

Makes me wonder if he knows John or Murray or Nick?
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OK, Jeff, you are starting to EMBARRASS the rest of us.  But keep up the good work!

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When it rains it pours (this has nothing to do with ETA). Nicely done Jeff.

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Congratulations to Jeff for publishing his first "first Author" paper from the lembixlab.  I predict it will not be his last.

Who knew that Jeff was in the vaccine game?
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Kar Men, John and Vance are hosting the Miami Axon Repair Meeting.  The first three days were great and we expect a strong finish tomorrow from hassan.  The social ACTIVITIES have been a blast.  


Congrats to Hassan for being an invited speaker at the Sydney Spinal Symposium.

  It is a bummer he didn't get to go to Sydney due to covid-19.  But cool they are excited about his work.
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Zheng Wang, our collaborator in the Computer Science Department, has won a special Maximizing Investigators' Research Award (MIRA) NIH Grant.  Way to Go! Read about it here.

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WE got some cool news this weekend!  Yukiko Nakamura, a former Post-doc who did beautiful work on L1 knock-in mice, has just been awarded a POSITION as a Senior Researcher at the Osaka Psychiatric Research Center.   Way to go Yukiko! 


Our latest computational paper shows that kinases are important sources of information that control the activity of regeneration ASSOCIATED Transcription Factors.  This INTERESTING result may help us understand why some kinase inhibitors have such a large effect on axon regeneration.   Thank You Prajwal, Matt and Stefan!

https://doi.org/10.1177/2472555220930697
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"One of the problems we face in the United States is that unfortunately, there is a combination of an anti-science bias that people are -- for reasons that sometimes are, you know, inconceivable and not understandable -- they just don't believe science and they don't believe authority," Fauci said in an episode of the US Department of Health and Human Services' podcast "Learning Curve" on Wednesday.  "So when they see someone up in the White House, which has an air of authority to it, who's talking about science, that there are some people who just don't believe that -- and that's unfortunate because, you know, science is truth."

I am not sure I would have said it that way, but I do think Dr. Fauci knows his stuff.  People and politicians IGNORE him at EVERYONE'S perial.

​I do think Florida is in for hard times.  Below is the CHOP model for Miami-Dade county.

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https://policylab.chop.edu/covid-lab-mapping-covid-19-your-community

May 31, 2020 was John Bixby's last day as Vice Provost for Research at U.M.  Today is the first day of his SABBATICAL.  He will be doing new and different things for the next year including research in the lemBixLab.  Welcome Back!

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Way cool graphic by Angelina Wu.  Thank you again.

LemBixlab logo gets a refresh:  an amazing young graphic artist, Angelina Wu, came up with a cleaner and more attractive version of NICK AND KAR MEN's original iconic logo.  Thank you Angie!


LemBIXLAB is part of the team on the NSF REU Computer Science program again!

Update - Another Covid-19 casualty - so sad we can't learn from CS undergrads this summer.  They bring so much knowledge and enthusiasm to the lab.  Hopefully we can do it in 2021 in a big way.

Burt Rosenberg has received news our NSF training grant is going to be renewed for three years.  This is fabulous.  We have had 4 undergrad students the last three summers.  They have done things like particle swarm optimization for drug target identification or deep learning to track animal movements.   If you want to learn how to apply CS skills to challenging real world projects and work with a very cool team please apply  to the program here .  You might also learn how to salsa.   

Reeve Foundation CSO visits the Miami Project and Lembixlab

Last week Ethan Perlstein and Amanda Zimmerman from the Christopher & Dana Reeve Foundation visited the Miami Project to learn about the diverse SCI portfolio that the faculty have developed over the years and the large number of clinical research projects and trials that are ongoing.  The LemBixLab has been working with the support of the UM Coulter Center to bring our kinase inhibitor project towards an investigational new drug (IND) submission to the US FDA.  Nathan and Amanda brainstormed with us about strategies to to bridge the gap to an IND.  We also discussed how to work together to attract venture philanthropy to go quickly to clinical trials.  It was a great experience.
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Vance, Ethan, Amanda, Hassan, and John on March 12, 2020 in the Lois Pope Life Center.

Nice story about Hassan in the Buoniconti Fund newsletter in December

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OK, I admit it is not LemBixLab News, but the CCS VizUM event is coming up.  It is my favorite event at UM each year.   Seriously.  It is why we want to be scientists when we grow up.

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Congratulations to Karim and Adam.  Their new grant will open the ODC-SCI to the SCI community​.  Thank you Craig H. Neilsen Foundation and Wings for Life Foundation.

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Jeff and Vance attended the recent Axon Repair meeting in Bonn hosted by Frank Bradke and founded by James Fawcett.  Jeff gave a great talk about his RNA-seq work.  Vance rambled on about forgotten adhesion molecule studies.

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Matt Danzi continues to amaze with his leadership in the collaboration with the de Giovanni lab.  Nature Neuroscience Co-First Author

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Recently Vance has been giving talks at SBI2, the Alicate Axon meeting and at the University of South Carolina.  The one thing that ties them all together has been rain and miserable weather.   OK Bonn - Bring it on!

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John has seen the light and realized life in the LemBixLab is more fun than life in the VPR office

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I wish I published as many papers as Hassan does.

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Oh, By The Way: Vic won an award for his outstanding poster

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Today is the last day of the dept of Computer Science REU program.  We had two amazing students; Juliana and Vic.  They were featured in a story about the program in the UM daily newsletter; NEWS@TheU

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Another week, another interview.  I blame John for this!
More seriously, the SCi data sharing community is a poster child

https://sr.ithaka.org/blog/emergent-data-community-spotlight/

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Back to work.  Kar Men and Nick were tired of the long cue at the library and bought a 3D printer to move faster on the pellet retrieval  project

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First test run: a cube.  Kind of boring but it worked

CS REUS DIG BIG DATA and Bachata - cue "Are You With Me?" (Lost Frequencies)

Burt Rosenberg from the CS department and I organized a party for the computer science REUs at my house with members of my lab.  The students are from Berkeley, Ga Tech, Chapel Hill, etc.  After a big dinner we had two short talks.  The first was about biomedical big data by Dr. Danny Cooper from Stephan Schürer’s group in Pharmacology.  The second one was by one of Albert Cairo’s students, Yuan Fang, about data visualization.  Then we had Bachata lessons, organized by Dr. Hassan Al-Ali from the Miami Project and his friends. The kids had a blast
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I am sorry but these conference organizers need to get with the AI thing.  I am not surprised to get invitations to any neuroscience or data science or screening meeting.  But Cereal biotech and breeding - come on!

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Congratulations to Kevin Park, Eric Bray and the rest of the team for the paper published on 6/26/19 . 

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Recently, there have been sightings of a USO (Unidentified skateboard object) around the LemBixLab.   Someone needs to investigate!

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Hassan is killing it in 2019 - as usual

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The Matt Danzi collaboration with the De Giovanni lab continues to bear fruit - Way to go Matt!!

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Kar Men is hanging with the heavies at the OSU SCI course - Nice!

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Vance went to the SCI 2020 meeting in Bethesda - He found it to be such a surprising experience he had to write a commentary about it.  It just appeared online in NRR (5/9/2019)

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Kar men, Jeff and Nick were Featured in a U.M. article on Big Data.

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Matt is killing it - another paper with The de Giovanni lab accepted!

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April 10, 2019:   Our long collaboration with the de Giovanni lab has produced another paper.  Way to go Matt!  Keep Going please

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​WHEN KAR MEN PRESENTED HER POSTER, FORMER LEMBIXLAB MEMBER, DR. ALEXIS TAPANES-CASTILLO, FROM ST. THOMAS UNIVERSITY CAME BY.

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March 5:  Kar Men is at the MPI Sunposium and Hassan is at a Keystone polypharmacology meeting.  How will we survive?


VAnce and Jae lee went to SCI 2020 in Bethesda.  It looks like NIH priorities in the sci field are going to be changing real soon.  you better get ready.

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Hey John, Yania asked me to help in the lab today - eat your heart out  ;-)

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VAnce gave a talk at the University of Alberta in Edmonton on 1/29/19.  He missed the Polar Vortex by a few 100 miles. thank goodness.  Went Fat Tire cycling with his amazing host, Karim Fouad.  Way fun

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The lab rats escaped to the Frost science museam today (1/26/19).  I am working on reviews and amendments - sigh - wish I was a lab rat too

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On Nov. 22, 2018, our validation study of neurotrophin-3-releasing chitosan in a rat SCI transection model appeared in experimental neurology in proof form.  this was the culmination of a two year effort involving faculty and staff from the University of Miami, Beihang university, Capital City university and tongji university.  Congratulations to the team for this important accomplishment.  we especially thank Martin oudega, Yan shi and Dan Liebl.  Professors xioaguang Li and yi eve sun were very brave to let us invade their labs to do this project. 

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On Nov 15-17 Vance was part of a fascinating meeting at the Romanian Academy of Science on neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology.  vance was responsible for the "psycho-Pharmacology" . LOL


Now you can see it in PubMed

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Hassan is the man; his team screened 400 million compounds on Primary neurons and found incredibly potent promoters of neurite growth - you got that right - clearly a new bar has been set by the lembix crew.  a great colloboration with Marc Giullanotti at TPIMS.  see the paper in ACS Med Chem 

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Nick, Kar men, John and Vance were in Prague to hang out with a bunch of DRG axon regeneration savants 

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Vance is going to Romania - lucky guy - 

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Matt's PhD project is out - nice!

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Jae Lee, Yan Shi and Vance  taught a light sheet microscopy workshop in Guangzhou China as part of the INRS meeting 

New FlAsh:  croatia 2, England 1 .  Professor bixby is in mourning  😢

John is very excited about the world cup!

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Saloni lives on in lembix land and stephanie is now sufficient - nice

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Vance has served on NIH, NSF and dOD study sections continuously for 30 years.  time to pass that responsibility on........  So long NDPR - a very smart group of scientists!

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We made a goofy lab photo to send to our friend Eli.  We thought we would share it.

Yan, Giulia, Yania, Tania, Nathan, John, Melissa, Danny, Koushik, Nick, and last but not least, Face Shield Man
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Vance and John were part of a symposium at sfn last year on SCI data sharing.  The sfn finally posted the video

Matt and Nick's review on epigenetics of axon regeneration just came out.  Nice job.  But vance and John have only co-authored 49 papers? A couple of slackers.

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Cool story about Hassan's STTR and Truvitech on the Miami Project web site


Giulia and Yan attended the Bitplane user Group Meeting at Stanford. 
​We anticipate much cooler filament tracing!

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Vance survived his trip to south africa - no face plants or charging lions

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Matt is rocking the bioinformatics world - another paper out from our collaboration with Simone Di Giovanni's lab.  You can look at the pdf here. 

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Cool story about Adam, Karim, and the SCI informatics problem in Lab Animal 

I am sorry but if a paper/chapter comes out in 2017, it is a 2017 publication.  13 in 2017 - most ever!   Thank you team!  

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Dario is first author on the chapter on HCA of neurons

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Hassan and Tania are famous: The Society for Neuroscience decided to feature our recent publication in their online science section.

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On Monday, Oct. 23, 2017, Matt Danzi successfully defended his PhD Dissertation: 
Examination committee: L>R: Stefan Wuchty, Vance Lemmon, john bixby, Matt Danzi, Nagi Ayad, Andrea Tedeschi, Stephan Zuchner.  Matt's family was in attendance.  


Congratulations to Matt, Andrew, Pantelis et al.  Love the “Team Science” thing

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On 9/27/17 Vance gave a talk at the stem cell institute at the University of minnesota.  while he was there he ran into tania, a former colleague of Giulia.  it is a small world

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It takes a long tome to get a patent, but it is nice when it issues

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#phd      @saloni

Saloni successfully defended her phd on 9/14/2017


​A new paper by Bray, Park, Tsoulfas and colleagues shows that axons from wild type retinal ganglion cells regenerate very long distances in a tortuous manner after injury but fail to cross the injury site.  goo.gl/oyAbZm   #neuron   #neuroscience  #theu   #miamiproject   #opticnerve  #regeneration

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Hassan came up with a very clever strategy and algorithm - this is not a shock, by the way - and did the scripting.  Roberta et al designed and performed the experiment. Yan Shi acquired the images.  Love that team science approach!

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​A commentary by Kevin Park and International colleagues just came out on the difficulty of doing optic nerve crush experiments.

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speaking of killing it!  NOA issued on 6/23/17 - sweet 

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LemBix is killing it in June: Congratulations to Hassan, Tania, Yania, Dario, Jessica, Matt and the VPR.  none of this would have happened without Yan and eli

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MAMI Yamasaki

Around 1981 I made a monoclonal antibody that stained axons in the chicken retina. The antibody turned out to be against NgCAM, the avian homologue of L1CAM.  I began studying L1 intensely and eventually had to clone a cDNA for L1 to move forward.  This had the unintended consequences of linking L1 to X-linked Hydrocephalus and a Japanese pharmaceutical licensing the sequence.  This lead to a trip to Kyoto in 1995 where I met Mami Yamasaki, a pediatric neurosurgeon who was very interested in X-linked hydrocephalus.  She came to my lab in Cleveland to work for a year and we had a wonderful collaboration for many years. Our families became friends and we would travel together.  She was the first female chair of a neurosurgery department in Japan, then a Vice-President of Osaka National Hospital and was a champion for making the medical workplace friendlier for women in child bearing years.  Unexpectedly, she passed away on June 13, 2017.  My family will miss her but always remember her.
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Adhesion molecules and inherited diseases of the human nervous system.
Kamiguchi H, Hlavin ML, Yamasaki M, Lemmon V.
Annu Rev Neurosci. 1998;21:97-125. Review.
PMID: 9530493

CRASH syndrome: mutations in L1CAM correlate with severity of the disease.
Yamasaki M, Thompson P, Lemmon V.
Neuropediatrics. 1997 Jun;28(3):175-8.
PMID: 9266556 

A paper describing the results of the SCI fair share meeting in Oct, 2016 in Bethesda was published in experimental Neurology on May 30, 2017

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SCI FAIR SHARE PAPER

The future is coming to the lembixlab with some serious pace

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The Lembix Lab is killing it

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Vance gave a bunch of talks (Univ of Iowa, Beihang University, Shanghai General Hospital and Tongji Hospital) in a 10 day span.  There was a lot of jet lag involved.  It was great to see our friend and colleague Ting.
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John is going to give a talk in a symposium at Rutgers on May 10th - cool
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April 21, John gave a talk at Pitt at Carl Lagenaur's retirement fest
April 20, 2017 Vance gave a talk at NIAAA in Bethesda
4/17/17  Jessica Lerch and Willie Buchser co-edit a special issue of Mol Cell Neuroscience on regeneration.  Murray Blackmore, Dario Motti, Danny Cooper and Giulia Zunino had papers in the special issue.  Sweet.  A lot of LemBix alum, way better than a Trifecta
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3/29/17   Vance's wins the "Provost's Research Funding Award".  It was handed to him by the Vice Provost for Research; Professor John Bixby.   LOL.
4/4/17  Party!
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3/1/17  Robbia Diaz, a Neuroscience Undergrad who has worked with Saloni the last 18 mts, has accepted an offer to enter the Cell Biology PhD program at UCSF.  Congratulations to Robbie AND Saloni for a great mentoring job.
2/28/17  We are excited to have a new PhD student, Nick O'Neil, join our lab.  During his rotation, he worked with Matt on a Next-Gen sequencing analysis project.  But now he wants to learn some wet lab stuff.
On Friday, Feb. 24, 2017, we got to catch up with Kim Madhwani, a student in the Leadership Alliance program who worked in our lab in 2015.  She is interviewing for PhD programs at Madison, Miami and Columbia.  Way to go Kim!
2/14/17  Danny Cooper gave a very well received talk at Stanford to the CEDAR SAB about his work using CEDAR to collect metadata for the LINCS DCIC
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2/4/17 Vance in Beijing to help launch the Thomas Institute, which is named after Thomas Südhof.  Dinner with the Mayor of Beijing
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The MIASCI paper was recommended by F1000 for a second time.  Douglas Katz liked the explanation of the difficulties of doing SCI research and recommended the article for teaching graduate students.  Cool.

Saloni rocking her poster presentation at sfn 2016
photo by Jae Lee, PhD

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Yesterday Martin Krzywinski gave an amazing talk at vizum2016.  So many insightful comments: "Scientists are ok with being confused".

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Dr. William Buchser is in Miami to give a lecture at the UM Biology department.  WE had the prodigal son to dinner to meet the newer lab members.

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Hassan was lead author on a chapter in a new book about injury models for CNS.  excellent job!

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Sept. 1, 2016: Great News!  Kevin Park and colleagues have received a UO1 to study retinal axon regeneration.  As part of the NEI audacious goals initiative the Park, Lembix and Bhattacharya labs will collaborate to test new genes and lipids in axon regeneration.  Other recipients of these awards include labs at stanford, Johns hopkins, yale, vanderbilt, and harvard.  Way to go Kevin!

LAB OUTING TO PAMM ON 7/28/2016 - THANK YOU CHIPI!

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Matt and Vance wrote a news and views for the embo Journal about a recent study on Cams inhibiting spinal cord axon regeneration.  what is up with that?

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Alison won the best PRESENTATION award at the Bio-Ontology SIG at the international Society for COMPUTATIONAL Biology meeting in Orlando.  She talked about Regenbase and integrating gene expression data. we are not surprised. 

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THE MIASCI PAPER WAS RECOGNIZED BY F1000!

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Yoshi Shibayama, a member of the Lemmon Lab at CWRU, was recently promoted to Professor of Pharmaceutics and Clinical Pharmacotherapy at the health sciences university of hokkaido.  Very cool - below is Yoshi and Vance in 2011 in Hokkaido.

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Hassan, Vance and John Visited NCATS on 6/9/16 to talk about target deconvolution and light sheet fluorescence Microscopy.  

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Saloni (and hassan) get the cover of Experimental Neurology vol 282

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John and his immunologist wife, Dr. Adkins, presented invited seminars in the Institute of Neuroscience and Physiology at the University of Gothenburg, Sweden. Afterward, the group went to a Swedish Chinese restaurant for some good Hunan cooking.

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Vance gave at lecture at the Ohio state SCI course on reproducibility in science, miasci and regenbase on 4/19/16.  He also got to see old lab members, jessica lerch and Dario Motti
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Miami dade brdige program: Family Science Sunday Rocks the Lembix Lab


Five years in the making! an ontology to describe axon regeneration.  As a bonus, there is a searchable knowledgebase.  The paper by Callahan et al published on line on 4/8/16.  

4/7/16 Ting's paper in Cell Press is on-line

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4/7/16  Saloni's paper in Experimental Neurology is on-line

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4/6/16  Hassan, John and Vance's project with Sanford Burnham Prebys florida, funded by the Coulter Foundation, kicked off today.

3/3/16  Alison's long awaited paper on the RegenBase Ontology was accepted.
​Double WooHoo!


The ABRF meeting was in Ft Lauderdale. the  Viral Vector Core and the High content Analysis core had Posters.  Both were selected as semi-Finalists for best poster Awards.  Pingping and Yan worked hard to get ready and gave awesome presentations.

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Hassan's commentary and Matt's Analgesia paper came out in the same issue of NRR - and of course Hassan had the cover.....

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Saloni took Marty Chalfie to Breakfast - sweet

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Hassan and Sam's phenotypic assay paper in experimental Neurology is live on the web

The opening of the CCS Data Visualization lab showed off LSFM movies from the Miami Project.  The Audience loved them

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Hassan Al-Ali's doppelganger, John Bixby and NIck Tsinoremas loving the Light Sheet movies

BD2K!  Stephan Schürer's DCIC data fest in Miami on Jan 19-21 was a "huge" success. Really Huge!  


Vance is part of a customer Panel for thomson reuthers sales meeting on 1/18/16 - clearly they were desperate to fill out the panel.

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Jae Lee had a commentary about the eNeuro LSFM paper on SfN NeurOnLine in Jan, 2016


The RegenBase project won the 2015 conquer Paralysis Now Trial and Error Prize for the MIASCI paper - Woohoo!


Vance went on bike tour of wynwood graffiti SPONSORED by shinola on 12/12/15.  The pics are here


Vance gave a talk at the Neuroscience center at UNC Chapel Hill on Nov. 12, 2015.  The faculty and students there are doing very exciting work and it was fun talking to Bryan Roth.


Hassan gave a webinar to the LINCS DATA Group on NOv 11, 2015.  It is AVAILABLE as an on-line video.  This is the best place to learn about his informatics pipleine.


Vance gave the opening Keynote at the ultramicroscopy meeting in Munster, Germany on 9/21/15.  There were great talks by DODT (Vienna), Erturk (LMU Munich), Ariel (Rockeffeller) and Kiefer (MPI Munster).  Jessica Lerch (OSU) gave a wonderful talk.  Way to go Jessica!

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VAnce Orgainzed a session and Yan Shi presented a poster on the astrocyte Assay at Society for Biological Imaging and informatics in Boston  Sept. 16-17, 2015


Hiroyuki Kamiguchi, a former post-doc with Vance in Cleveland, had a ​​​science paper recently on a Glycerophospholipid that is IMPORTANT in axon guidance in the spinal cord. 


Hassan's ACS paper makes the Cover! August 2015

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Sam's paper published on line - Woohoo!
ASSAY and Drug Development Technologies


Sam Beckerman Defends his PhD - July 17, 2015
Congratulations all around!

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​Suni Lee, a former post-doc in the LemBix Lab, had a Science paper about EPILEPSY recently.  Very Cool.  


Saminda Abbeyruwan defends his phd in computer science - july 6, 2015
Now he works for cisco.  Lucky for them, Bummer for us.

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